Controlled release particles, or emulsion systems to combine and protect biocompatible active ingredients. Reduced costs through the elimination of waste. Designed to fully comply with FDA requirements.
The pharmaceutical industry is one of the most research intensive sectors in the world. The high cost and long time frames associated with bringing pharmaceutical products to market mean that companies in this sector need proven, reliable suppliers who will accompany them from the start of formulation development to final drug marketing. In the generic markets, where time and cost are especially critical, suppliers need to provide simple, cost effective solutions to complex formulation issues.
• Product innovation - pH trigger, enzymatic release or diffusive systems for drug delivery.
• Enhanced processability - Allows formulation with ingredients that are usually incompatible.
• Targeted release of actives in the intestine, bypassing stomach acid, which may reduce efficacy.
• Injectable subcutaneous slow release systems.
• Taste masking.
• Higher loading of active than traditional encapsulation methods, such as spray drying.
Micropore is uniquely positioned via our patented processes and systems to work with pharmaceutical clients. Our technology offers the ability to produce mono-dispersed particles for controlled release applications and we have significant expertise using the biocompatible polymers, poly(lactic-co-glycolic acid) (PLGA) as well as poly(lactic acid) (PLA), Polycaprolactone (PCL), etc.
Micropore's processes are designed to be scalable - from laboratory formulation testing to production tonnages. This enables meaningful laboratory data to be used to scale a process to production volumes.
The system is easy to control and has a lower factory space requirement than conventional stirred tank technology.
The Micropore patented manufacturing techniques provide uniform droplets and particles and lead to 100% production success in the desired size range. There is no waste compared to conventional manufacturing techniques. Using Micropore technology results in significantly lower energy and waste disposal costs.
Reliability and Reproducibility:
Micropore’s technology enables highly reliable and reproducible production of batches of materials. This is especially important in production environments when pH is adjusted; our techniques lead to no 'bad batches’ to be disposed of.
The Micropore systems are easy to control and do not require time consuming and costly specialist operator training.
Stainless Steel benefits:
The Micropore equipment is constructed entirely of food grade stainless steel with industry standard hygienic fittings. Additional standards of finish are available for pharmaceutical use. The 100% stainless steel equipment can be run at elevated temperatures.
Micropore’s equipment can be fully enclosed to ensure environmental segregation and product isolation.
The low shear and gentle conditions used during membrane emulsification are ideal to prevent damage to protein based therapies and other sensitive active ingredients.
cGMP designs for production are available.
High Viscosity Materials:
Micropore technology is ideal for the production of creams and pastes and provides exceptionally good mixing even of high viscosity materials.
We provide a service to develop the best release profile for your ingredients and products; using our expertise in encapsulation and formulation technology based on our membrane emulsification processes.
Europe, Middle East, Asia
Americas & Canada